| アイテムタイプ |
紀要論文 / Departmental Bulletin Paper(1) |
| 公開日 |
2009-07-25 |
| タイトル |
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タイトル |
エンドトキシン誘発播種性血管内凝固に対する糖尿病の影響 |
| タイトル |
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タイトル |
Influence of diabetes for disseminated intravascular coagulation induced with endotoxin |
|
言語 |
en |
| 言語 |
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|
言語 |
jpn |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
departmental bulletin paper |
| ID登録 |
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|
ID登録 |
10.14993/00000460 |
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ID登録タイプ |
JaLC |
| 著者 |
今村, 友美
宮本, 幸代
高橋, 志乃
堀江, 登
Miyamoto, Sachiyo
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| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
This paper is a study concerning diabetes that have a tendency for blood coagulation whether it was a risk of sudden death. We made a diabetes model mouse by intraperitoneal injection of streptozotocin (STZ), and we caused disseminated intravascular coagulation (DIC) by doing an intra-tailvenous injection of endotoxin (ET) to the mouse. After injection of STZ, a weight loss, decrease of intra-abdominal fat, polyphagy, polyposia are induced and they are the main symptoms of diabetes. Furthermore, with an ET injection to the mouse, it showed increase of weight such as the lung and the liver and extension of PT time with the blood clot formation, and that it was it in a blood coagulation tendency was confirmed by these symptoms. Then, the mouse showed a decrease of plasminogen activator activity in the lung. Therefore, fibrinolysis system was enhanced in the mouse, and it was suggested that a symptom of DIC turned worse under a state of diabetes. |
| 書誌情報 |
武庫川女子大学紀要. 自然科学編
巻 54,
p. 19-24,
発行日 2006-03-31
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| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
0916-3123 |
| 書誌レコードID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AN10187277 |
P19-24.pdf (529.9 kB)
