@article{oai:mukogawa.repo.nii.ac.jp:00000692,
 author = {田中, 繁宏 and TANAKA, Shigehiro},
 journal = {健康運動科学},
 month = {Dec},
 note = {Athletes occasionally have problems in training while having a chronic cough. Cough is a protective reflex of the respiratory tract that is mainly used to clear the upper airways. Chronic cough lasting for more than 8 weeks is commonly seen by the out patient respiratory or laryngeal physicians. The extrinsic causes include exposure to cigarette smoke and exposure to environmental pollution, especially particulates. Diseases causing chronic cough include cancer, tuberculosis, asthma, eosinophilic bronchitis, gastroesophageal reflux disease （GERD）, postnasal drip syndrome, allergic rhinitis, sinusitis, chronic obstructive pulmonary disease, pulmonary fibrosis, and bronchiectasis. Physicians should always be aware of the past history of the patients. We can not determine the cause of chronic cough in some cases. Chronic cough is often associated with an increased response to tussive agents such as capsaicin. Some kinds of changes in intrinsic and synaptic excitability in the brainstem, spine, or airway nerves can stimulate the cough reflex. Irritative and inflammatory airway mucosal changes in patients with nonasthmatic chronic cough could represent the cause or the common response to repetitive coughing. Effective control of the cough requires controlling the disease causing the cough and the desensitization of the cough-related pathways. Therefore, the patients with chronic cough can be treated with ease. Bronchopulmonary C-fibers and acid-sensitive, capsaicin-insensitive mechanoreceptors innervating the larynx, trachea and large bronchi regulate the cough reflex. These vagal afferent nerves may interact centrally with sensory input arising from afferent nerves innervating the intrapulmonary airways or even extrapulmonary afferents, and so those innervating the nasal mucosa and esophagus to produce a chronic cough or enhanced cough responsiveness. The treatment for cough variant asthma （CVA） is basically composed of inhaled corticosteroids and β2-stimulants, which is similar to the medications for asthma. Allergic rhinitis is treated with H1anti-histamine agents. Inhaled ciclesonide（ corticosteroid） combined with tulobuterol（ β2-stimulant） is recommended for the treatment of CVA because these agents are likely to act on peripheral airways. Chronic cough by GER is mainly treated with proton pump inhibitors or H2 blockers.},
 pages = {1--5},
 title = {アスリートと咳（慢性咳嗽を中心に） ―最近の研究の動向―},
 volume = {1},
 year = {2010},
 yomi = {タナカ, シゲヒロ}
}