@article{oai:mukogawa.repo.nii.ac.jp:00001033, author = {根岸, 裕子 and 川上, 浩平 and Negishi, Hiroko and Kawakami, Kohei}, journal = {武庫川女子大紀要. 自然科学}, month = {Mar}, note = {Twenty-four-hour ambulatory blood pressure monitoring has focused on the incidence of hypertension-related end organ damage. This study analyzed 24-hour blood pressure in normotensive Wistar Kyoto rats(WKY), spontaneously hypertensive rats( SHR), and stroke-prone SHR( SHRSP), which are used as a model of hypertension. Each rat at 12 weeks of age was used for 24-hour blood pressure monitoring for 7 days. This ambulatory blood pressure monitoring was conducted using a telemetry system. Twenty -four-hour systolic and diastolic blood pressures in SHRSP( n=5) were significantly higher than in SHR( n=5) and WKY( n=5), but the heart rate did not change among these strains. SHRSP showed the non-dipper phenomenon for 2 days. From these results, the circadian rhythm in 24-hour ambulatory blood pressure of SHRSP was different from those in SHR and WKY, possibly due to marked hypertension.}, pages = {1--5}, title = {Spontaneously Hypertensive Rat, Stroke-prone Spontaneously Hypertensive Rat 及びWistar Kyoto Rat の24時間血圧概日リズムの基礎的検討}, volume = {64}, year = {2017}, yomi = {ネギシ, ヒロコ and カワカミ, コウヘイ} }